Reflective Practive

Allergy and allergen components

ImmunoCAP has over 650 different allergens and 90 allergen components for sensitive and precise quantitative detection of allergen-specific IgE antibodies. Serum and plasma (EDTA or heparin) samples from venous or capillary blood can be used for ImmunoCAP testing, and blood can be collected using standard procedures. Specimens can be stored at room temperature for shipping purposes only; otherwise specimens can be stored at 2-8 °C for up to one week, or -20 °C for longer. Specimens should not be repeatedly frozen and thawed. Note: Blood samples for testing ImmunoCAP drugs and venom should be collected during or close to the event, preferably not later than 6 months after exposure. If the test result is negative and an IgE-mediated reaction is still strongly suspected, it is advisable to draw a new sample and repeat the test at 5 to 6 weeks.

Product catalogue

Click below to download a copy of the product catalogue

Allergy & autoimmunity product catalogue 2018

Interpreting results

IgE antibodies appear in human serum and plasma as a result of sensitisation to a specific allergen. Measurement of circulating IgE antibodies provides an objective assessment of sensitisation to an allergen. In general, low IgE antibody levels indicate a low probability of clinical disease, whereas high antibody levels to an allergen show good correlation with clinical disease. From an allergen source, single allergen components can be produced. Sensitisation to these components is then measured individually in separate tests, helping to pinpoint, on an exact molecular level, which component the patient is sensitized to. This information provides the basis for a refined diagnosis of the allergy. Different components are associated with different degrees of risk:
CCDs: Cross-reactive carbohydrate determines PR-10: Pathogenesis related family number 10 nsLTP: Non-specific lipid transfer proteins

Are you a laboratory professional?

This educational website, provided by Thermo Fisher Scientific, ImmunoDiagnostics Division, has been produced in partnership with the Institute of Biomedical Science as a pioneering venture to promote excellence in laboratory practice using education and continuing professional development (CPD) resources.

The information contained within this website is intended for laboratory professionals.

By entering this website you are confirming that you are a laboratory professional.

Enter Website

We use cookies on our website to provide you with a good experience. You may choose to accept or decline our cookie usage. Our website may not be usable if you decline cookie usage. Click here to learn more about how we use cookies on our website.

Are you interested in receiving information from Thermo Fisher Scientific?

Yes, I would like to receive:

By submitting this form, you consent to the Thermo Fisher Scientific collecting and processing your personal data

We also want to inform you we are cooperating with Veeva Systems Inc.’s Open Data syndicated database to ensure the contact information is always up to date. This means that subscribers to this database may access your professional contact information (name, job title, institution name and address) and if any user report a change to these basic public information this will be shared with all through the database. All relevant Veeva Systems Inc. servers are located inside the European Union.
For any privacy questions or concerns, or to exercise your rights as a data subject as described in our Privacy Policy, please contact us at dataprivacy@thermofisher.com

Your details have successfully been submitted.