The Threshold

What may seem as the obvious trigger may just be the "tip of the iceberg". Since most atopic individuals are allergic to more than one allergen, it is important to identify all the allergens that contribute to the symptoms to ensure optimal symptom relief.

  • Up to 80% of allergic patients are sensitized to, on average, 3 allergens1,2
  • Food and inhalant allergens may have additive effects3,4

Exposure Reduction

Patient experiences symptoms when threshold is exceeded

The allergen symptom threshold is the point at which the cumulative alllergen load leads to symptoms4


After exposure reduction

By reducing exposure to modifiable triggers, symptoms can be avoided3,4

Identifying the sensitising allergens will help you outline an avoidance plan to keep patients below symptom threshold

History alone is not enough

Allergen testing improves accuracy of results vs. patient history alone5


Click to learn more about the benefits of testing in:

Identifying the sensitising allergens will help you outline an avoidance plan to keep patients below symptom threshold


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  1. Ciprandi G, et al. Eur Ann Allergy Clin Immunol 2008;40:77-83.
  2. Petersson CJ, et al. Sensitization profile in undiagnosed children with skin and respiratory allergy-like symptoms in primary care. Abstract presented at WAO, Buenos Aires, Argentina 6-10 December 2009.
  3. Simpson A, et al. J Allergy Clin Immunol 2005;116:744-9.
  4. Stoltz DJ, et al. Clin Exp Allergy 2013;43:233-41.
  5. Wickman M. Allergy 2005;60(suppl 79):14-18
  6. Eggleston PA. lmmunol Allergy Clin North Am 2003;23(3):533-547
  7. Smith HE, et al. J Allergy Clin Immunol 2009;123:646-650. National Institute for Health and Care Excellence. Food allergy in children and young people (CG116). 2011

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